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CBD: Is it addictive
While current evidence indicates that you won’t develop a CBD addiction, it is possible to have an adverse reaction to cannabidiol. Talking to your doctor first and starting with a low dose can reduce the risk of unwanted side effects.
Is CBD Addictive?
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Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
Because marijuana can be addictive, particularly when it is used heavily and at high doses, you might wonder if CBD addiction is also possible. CBD (cannabidiol) is one of the many compounds found in cannabis. Products containing CBD have grown in popularity in recent years, found in everything from gummy supplements to post-workout smoothies to CBD-infused pillows.
CBD’s burgeoning popularity has been fueled in part by the compound’s purported mental health-boosting properties. However, some people may hesitate to use such products for fear that CBD might have the same potential for addiction as cannabis.
This article discusses whether CBD addiction is something to worry about. It also covers some of the other possible concerns you might have when taking CBD.
Is CBD Addictive?
Drug addiction is defined as a compulsive need to use a substance and an inability to stop using it despite negative consequences.
Substances that lead to dependence and addiction affect the pleasure centers of the brain, often making it so that people need to consume a substance to avoid experiencing symptoms of withdrawal. In many cases, people may also need to use more and more of a drug in order to continue experiencing the same euphoric effects that they initially felt.
Tetrahydrocannabinol (THC) is the psychoactive compound in cannabis that produces the high associated with marijuana. When administered, THC travels to the brain via the bloodstream and attaches to the endocannabinoid receptors found in areas of the brain that are associated with things such as pleasure, movement, memory, and thought.
While cannabidiol also interacts with the body’s endocannabinoid system, CBD does not have the same intoxicating properties that THC has. Research suggests it has a good safety profile and is well tolerated at doses up to 600mg to 1,500 mg.
Unlike THC (tetrahydrocannabinol), CBD does not produce psychoactive effects. And while marijuana use can lead to dependence, current research suggests that CBD is not addictive.
According to the World Health Organization, in humans, CBD exhibits no effects indicative of any abuse or dependence potential…To date, there is no evidence of public health-related problems associated with the use of pure CBD.
A 2017 study published in the Journal of Drug and Alcohol Dependence suggested that CBD has the same potential for dependence as a placebo pill.
However, it is important to note that many CBD products may contain some level of THC. Federal law requires that hemp-derived CBD products contain less than 0.3% of THC. However, research has found that 70% of CBD products contain significantly more THC than their labels suggest.
While CBD is not addictive, THC is. Evidence suggests that people can develop a tolerance to THC and may experience withdrawal symptoms. Physical dependence on THC is more likely among people who use high-THC cannabis strains.
CBD Might Help Treat Addiction
Some evidence suggests that CBD may actually be helpful for treating drug addiction and addictive behaviors. For example, while the research is still scarce and preliminary, studies have found that CBD shows promise in the treatment of cocaine and methamphetamine addiction.
A 2015 review of available preclinical and clinical data found that CBD had therapeutic properties in the treatment of cocaine, opioid, and psychostimulant addiction. Evidence also indicated that it might have benefits in the treatment of tobacco and cannabis addiction.
A 2019 study found that cannabidiol might help reduce drug cravings, paranoia, impulsivity, and withdrawal symptoms associated with crack-cocaine addiction.
While promising, more research is needed to understand how CBD might be utilized for the treatment of substance use disorders.
Effects of CBD
While CBD does not have psychoactive properties, it does have a variety of effects. Its potential impact on mental health conditions such as anxiety and depression has been a specific point of interest for many.
In addition to mental health benefits, some research indicates that CBD might be helpful for reducing pain, relieving nausea, and treating inflammation. The World Health Organization also suggests that CBD may be helpful for treating conditions such as Alzheimer’s disease, arthritis, cardiovascular disease, and diabetes.
Some of the potential uses are listed below.
Seizures
Research has found that CBD may help reduce seizures caused by epilepsy. A 2018 study of children and adults with treatment-resistant epilepsy found that the use of CBD was associated with reductions in the frequency and severity of seizures.
In 2018, the FDA approved Epidiolex, a CBD solution, for the treatment of rare, severe forms of epilepsy.
Anxiety
Research also suggests that CBD may be helpful for alleviating symptoms of anxiety. For example, one study found that cannabidiol was useful for reducing symptoms of generalized anxiety disorder (GAD), panic disorder, post-traumatic stress disorder (PTSD), and social anxiety disorder.
Depression
Studies also suggest that CBD may have potential in the treatment of depression. For example, one study found that CBD influences how the brain responds to serotonin, which may have an antidepressant-like effect.
What the Research Says
While CBD does not appear to be addictive and may have some benefits, one large-scale review concluded that there was not enough evidence to support the use of CBD as a treatment for mental health conditions.
This doesn’t mean that CBD might not be helpful. It means that more studies are needed to determine what CBD might treat, when it is best used, and what dosage people should take.
Side Effects and Other Concerns
Current evidence suggests that CBD use does not lead to addiction and that the substance may have a number of health benefits. However, it is also important to be aware that CBD does have some potential side effects.
Some side effects that may occur when taking CBD include:
- Anxiety
- Changes in appetite
- Dizziness
- Drug interactions
- Drowsiness
- Dry mouth
- Gastrointestinal problems
- Mood changes
- Nausea
Research indicates that CBD is generally well-tolerated up to doses of around 600 mg and as high as 1500 mg. However, it can often be difficult to determine how much CBD you are actually taking. According to one study, 43% of commercially-available CBD products contain substantially more cannabidiol than indicated on the label.
The National Center for Complementary and Integrative Health cautions that CBD may be harmful to some people. In some studies, the use of Epidiolex was linked to liver problems and drug interactions.
While such issues can be managed when taking a prescribed medication under doctor supervision, self-administered CBD could potentially have the same harmful effects, particularly since it can be difficult to determine how much CBD many products actually contain.
CBD products may also contain higher levels of THC than stated on the label. This can be concerning if you are trying to avoid THC.
Recap
While current evidence indicates that you won’t develop a CBD addiction, it is possible to have an adverse reaction to cannabidiol. Talking to your doctor first and starting with a low dose can reduce the risk of unwanted side effects.
A Word From Verywell
CBD doesn’t appear to be addictive, but that doesn’t mean that it is right for everyone. If you are thinking about trying CBD, discuss it with your doctor first. Be sure to tell your healthcare provider about any other medications you might be taking in order to prevent any potential drug interactions. Watch for side effects and don’t take more than the dose that your doctor recommends.
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
- American Society of Addiction Medicine. Definition of addiction.
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- World Health Organization. Cannabidiol (CBD): pre-review report, agenda item 5.2.
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- Food and Drug Administration (FDA). FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy.
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By Kendra Cherry, MSEd
Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the “Everything Psychology Book.”
CBD: Is it addictive?
While current scientific evidence suggests that heavy cannabis use may increase the risk of dependence in some people, CBD by itself does not appear to be addictive. However, research into the long-term effects of CBD usage is still in its early stages.
Researchers, healthcare professionals, and academics continue to explore the potential benefits of cannabidiol (CBD). CBD is a cannabinoid and one of over 400 chemical compounds present in the Cannabis sativa plant.
Unlike its counterpart, delta-tetrahydrocannabinol (THC), CBD does not have psychoactive effects. However, people may wonder whether CBD is addictive.
In this article, we discuss what the research says about the addictive potential of CBD.
CBD, by itself, does not appear to have addiction-related effects. This may be because CBD does not produce intoxicating effects.
According to a 2017 Pre-Review Report, the World Health Organization (WHO) states that “evidence from well-controlled human experimental research indicates that CBD is not associated with abuse potential.”
The results of a small 2016 study of 31 adults show that while active THC produced substantial physical and psychological effects, such as rapid heart rate and euphoria, CBD did not affect heart rate, blood pressure, or cognitive function.
CBD also performed similarly to a placebo on self-reported feelings of intoxication. Conversely, the THC group reported feeling euphoric and sedated.
Not only is CBD not addictive, but it may even help treat drug addiction.
Preliminary evidence suggests that CBD might lower the likelihood of developing cocaine and methamphetamine use disorders. It may also help prevent relapse after a period of detoxification and sobriety.
The authors of a 2015 review found evidence that CBD may also help treat nicotine and cannabis addiction.
For more information and resources on CBD and CBD products, please visit our dedicated hub.
CBD does not create the ‘high’ effects that many people associate with cannabis use and may help treat a wide range of medical conditions.
CBD is a widely researched alternative treatment for epileptic seizures.
Reduces epileptic seizures
In a 2018 clinical trial, 72 children and 60 adults with treatment-resistant epilepsy received 5–50 milligrams per kilogram of body weight (mg/kg) of CBD daily.
The researchers reported that two-thirds of the participants experienced at least a 25% reduction in seizure frequency while receiving CBD treatment.
In 2018, the Food and Drug Administration (FDA) approved Epidiolex, the first pure-CBD anti-seizure treatment. The FDA approved Epidiolex for treating rare forms of epilepsy, including Dravet syndrome and Lennox-Gastuaut syndrome.
The FDA cites clinical evidence suggesting people with Dravet and Lennox-Gastaut syndromes taking Epidiolex alongside other seizure medications had fewer seizures than those taking a placebo and other seizure medications.
Might reduce anxiety
CBD might also help reduce anxiety. However, current research shows conflicting evidence, and researchers need to conduct additional high-quality controlled trials to verify these findings.
In a 2019 study , researchers examined CBD’s effects on 72 adults with anxiety and sleep problems. Within the first month of treatment, 79.2% of participants reported reduced anxiety symptoms, and 66.7% reported improved sleep quality.
In a 2017 study , 60 adults with no history of anxiety, mental illness, or drug dependence received 100, 300, or 900 mg doses of CBD or a 1 mg dose of clonazepam before giving a speech.
Those who took a 300 mg dose of CBD saw significantly reduced social anxiety scores before, during, and after public speaking. Anxiety levels remained high in those who took the 100 and 900 mg CBD dose. Clonazepam reduced blood pressure or heart rate, but CBD had no physical effects.
Relieves chronic pain
A 2020 study found that full-spectrum hemp-extracted CBD reduced neuropathic pain in mice.
Another recent study based in New Zealand examined CBD use among 400 people with chronic pain and mental health conditions. The participants reported improved quality of life outcomes after using CBD.
The researchers also stated that CBD use was not associated with significant side effects. In fact, participants reported improvements in sleep and appetite.
The authors of one 2020 review state that cannabis-based treatments may offer a potential alternative to opioid-based pain medication.
However, the authors draw attention to the fact that most studies use a combination of THC and CBD. As a result, assessing the pain management benefits of CBD alone can be challenging.
Other effects of CBD
Other potential effects of CBD that have only been demonstrated in animals and require further investigation include:
- reducing inflammation
- regulating the immune system
- suppressing nausea
- inhibiting cancer